Microanalysis of Amino Acids. I. A New Modified Ninhydrin Reagent.
نویسندگان
چکیده
منابع مشابه
A modified ninhydrin reagent for the photometric determination of amino acids and related compounds.
The photometric ninhydrin method described previously (1) for use in the chromatography of amino acids has been the subject of further study during the development of the Dowex 50-X4 procedure (2). The adjustment of the pH of the effluent fractions prior to analysis required by the earlier method has been largely eliminated by increasing the strength of the buffer in the reagent 5-fold. A secon...
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Our purpose is to show by means of a quantitative method for determination of hydrindantin derivatives that previous concepts of the mechanism of the reaction of ninhydrin with amino acids are inadequate or erroneous, and to show facts supporting a new concept. The main facts are as follows: (a) Hydrindantin forms when amino acids react with ninhydrin (Ruhemann (1) ; Abderhalden (2)) ; (b) it r...
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Derivatives of amino acids bearing a porphyrin moiety on a side chain were synthesized by coupling a porphyrin to a glutamic acid side chain; the utility of these compounds was demonstrated by their use in solid-phase synthesis of a peptide bearing a cationic porphyrin and by studying its DNA-binding properties.
متن کاملDetermination of certain amino-acids by ninhydrin oxidation to volatile aldehydes.
The quantitative determination of amino-acids in a small sample is an important aim in protein research in its present stage. Especially in the U.S.A. and in Great Britain great advances have been made in this field during recent years. In this connexion the lecture by Chibnall (1946) may be cited. Nevertheless, the elucidation ofthe amino-acid composition of proteins is still a difficult task ...
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ژورنال
عنوان ژورنال: Pharmaceutical Bulletin
سال: 1957
ISSN: 0369-9471,1881-1345
DOI: 10.1248/cpb1953.5.363